Protein Folding and Conformational Diseases/ Bioinformatics
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In-house software:
SolupHred
A web server for the prediction of pH-dependent aggregation of IDPs.
Pintado, C.; Santos, J.; Iglesias, V. and Ventura, S. SolupHred: A Server to Predict the pH-dependent Aggregation of Intrinsically Disordered Proteins. Bioinformatics 2020, btaa909. doi:10.1093/bioinformatics/btaa909
DispHred
A web server for the prediction of pH-dependent order-disorder transitions of IDPs.
Santos, J.; Iglesias, V.; Pintado, C.; Santos-Suárez, J.; Ventura, S. DispHred: A server for the prediction of pH-dependent order-disorder transitions of intrinsically disordered proteins from the primary sequence. IJMS 2020, 21, 5814. doi: 10.3390/ijms21165814
SGnn
A server for the prediction of prion-like domains recruitment to stress granules upon heat stress.
Iglesias V, Santos J, Santos-Suárez J, Pintado-Grima C and Ventura S (2021) SGnn: A Web Server for the Prediction of Prion-Like Domains Recruitment to Stress Granules Upon Heat Stress. Front. Mol. Biosci. 8:718301. doi: 10.3389/fmolb.2021.718301
DispHScan
A multi-sequence web tool for predicting protein disorder as a function of pH and spot folding transitions in large datasets.
Pintado-Grima, C.; Iglesias, V.; Santos, J.; Uversky, V.N.; Ventura, S. DispHScan: A Multi-Sequence Web Tool for Predicting Protein Disorder as a Function of pH. Biomolecules 2021, 11, 1596. https://doi.org/10.3390/biom11111596
CARs-DB
CARs-DB: a database of Cryptic Amyloidogenic Regions in Instrinsically Disordered Proteins.
Pintado-Grima C., Bárcenas O., Manglano-Artuñedo Z., Vilaça R., Macedo-Ribeiro S., Pallarès I., Santos J. and Ventura S.CARs-DB: a database of Cryptic Amyloidogenic Regions in Instrinsically Disordered Proteins.Front. Mol. Biosci., 9:882160 (2022). https://doi.org/10.3389/fmolb.2022.882160